Final Day: Rewards Members earn 10% back on SkinCeuticals + Complimentary SkinCeuticals $24 Gift with ANY purchase.
FREE US Shipping $50+ Ask an Expert 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

Rewards members earn 2950 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$295.00

Or 4 interest free payments of $73.75 with sezzle


In stock | Usually dispatched within 24 hours

Image 1 - A side-by-side comparison shows the face of a 60-year-old female with improvements in skin texture after two weeks, labeled BASELINE on the left and +2 WEEKS on the right, with highlighted areas indicating changes; text below reads Female, age 60, Fitzpatrick Skin Type II. Unretouched photos, taken in standard lighting. Individual results may vary.
Image 2 - Side-by-side comparison of a 68-year-old womans face, showing improvements in skin texture and appearance at baseline and after 24 weeks; text includes IMPROVEMENTS AT WEEK 24, +BASELINE, +24 WEEKS, Female, age 68, Fitzpatrick Skin Type II. Untouched photos, taken in standard lighting. Individual results may vary.
Image 3 - Image of SkinMedica skincare products arranged in a line with labels: AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA5 Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen. Header text reads Complete Your SkinMedica® Method Routine.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.55 stars out of a maximum of 5

5 stars rating 441 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 20 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

TNS serum

4 stars out of a maximum of 5

GREAT product….one of the ports on mine isn’t working though….I need to figure out how to get that evaluated

by Meg Verified Purchase

Was this helpful?

Great product

5 stars out of a maximum of 5

Skinmedica is a great line . Tns is very effective. And I pair it with HA5. Also from Dermstore I have been using for many years it keeps my skin plumped and hydrated!

by linda Verified Purchase

Was this helpful?

Expensive but can tell the difference

4 stars out of a maximum of 5

It’s a really expensive cream.  But I can tell the difference since I started using it.  Skin is more glowy and plump.  I will buy again.

by Jennifer Verified Purchase

Was this helpful?

TNS

5 stars out of a maximum of 5

This stuff is amazing. Expensive— yes. Worth ever penny? Absolutely.

by VesperNC Verified Purchase

Was this helpful?

Ms

4 stars out of a maximum of 5

Love this product. I’ve been using for about 3 years and can always tell a huge difference if I take a break from it or run out. Great for texture and fine lines.  However, my recent bottle wasn’t dispensing from both chambers. 

by amsbeauty Verified Purchase

Was this helpful?

So far, so good

5 stars out of a maximum of 5

Purchased due to a recommendation on behalf of my dermatologist. Works great after my retinol, layered with moisturizer. Also, enjoying the creamy consistency. Will update after 3 months of consistent use. 

by sarah Verified Purchase

Was this helpful?

Great product

5 stars out of a maximum of 5

I’ve been using TNS for years and love the product.   It is moisturizing and firming and makes your skin feel great.  

by Wendi Verified Purchase

Was this helpful?

SkinMedica is the real deal!

5 stars out of a maximum of 5

I had taken a break from SkinMedica products - really just for a change of pace, variety, product junkie etc. Even though I use other good products like La Mer, Sisley, Tatcha, I found myself missing the effectiveness and just spot on work of SkinMedica. They are a luxurious product but a workhorse at the same time. Love this serum and SkinMedica products. Glad I’m back! 

by Linda Verified Purchase

Was this helpful?

It DOES what it says! Added to skincare routine, W/in mth…noticed.!

5 stars out of a maximum of 5

Worth the price To work on All areas of A 50yr old face! Along with daily other routine for face.

by Mary Verified Purchase

Was this helpful?

I can tell the difference

5 stars out of a maximum of 5

A friend told me I should buy this and I'm glad I did. I've been using it for about a month and I can definitely tell it's working!

by Jennifer Verified Purchase

Was this helpful?