Get a complimentary $24 SkinCeuticals gift with ANY purchase. SHOP NOW
FREE US Shipping $50+ Ask an Expert 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

Rewards members earn 2950 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$295.00

Or 4 interest free payments of $73.75 with sezzle


In stock | Usually dispatched within 24 hours

Image 1 - A side-by-side comparison shows the face of a 60-year-old female with improvements in skin texture after two weeks, labeled BASELINE on the left and +2 WEEKS on the right, with highlighted areas indicating changes; text below reads Female, age 60, Fitzpatrick Skin Type II. Unretouched photos, taken in standard lighting. Individual results may vary.
Image 2 - Side-by-side comparison of a 68-year-old womans face, showing improvements in skin texture and appearance at baseline and after 24 weeks; text includes IMPROVEMENTS AT WEEK 24, +BASELINE, +24 WEEKS, Female, age 68, Fitzpatrick Skin Type II. Untouched photos, taken in standard lighting. Individual results may vary.
Image 3 - Image of SkinMedica skincare products arranged in a line with labels: AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA5 Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen. Header text reads Complete Your SkinMedica® Method Routine.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.55 stars out of a maximum of 5

5 stars rating 441 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 20 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Transformative

5 stars out of a maximum of 5

I've been using this for only 6 weeks and there's been a noticeable improvement in my laugh lines and crow's feet. My dark spots have also dramatically faded. It's pricey but effective. 

by Lisa Verified Purchase

Was this helpful?

Love it!

5 stars out of a maximum of 5

I really love the texture of this serum. It’s not heavy and absorbs quickly. I will continue using it as I’ve heard great things about it. 

by Ari Verified Purchase

Was this helpful?

Amazing! Worth every penny

5 stars out of a maximum of 5

Yes, it's expensive. The price used to hold me back, however, the results are fantastic and for that reason worth every penny. I am on my third bottle of the serum. my 47 year old skin has never looked better. A life saver for my sensitive neck. I did sign up for the auto replenish monthly so I never run out and save some money as well. For those that mention pilling, pat on additional products and if you wear makeup do the same. Problem solved.

by Maricela Verified Purchase

Was this helpful?

Love this stuff

5 stars out of a maximum of 5

This is one of my top 2 skin care product must haves. I miss the old formula that also contained vitamin C, but the TNS growth factor is still worth it to use this product. 

by Srr1111 Verified Purchase

Was this helpful?

Leaves waxy film

3 stars out of a maximum of 5

Not really impressed with this product, especially for the price. It leave a waxy film so I can not use it during the day under my make up. At night it leaves oily residue on my pillowcase. I don't really see any improvement on my skin either. Don't think I will be ordering this product again. May try one of the other serums recommended

by Angela Verified Purchase

Was this helpful?

Let Down

2 stars out of a maximum of 5

This was a let down. No noticeable changes after completing the entire bottle. The TNS Complex single pump is by far the best.

by Anna, RN

Was this helpful?

Great Serum!

5 stars out of a maximum of 5

Love the feel. Absorbs easy. Great hydration!

by Brittany Verified Purchase

Was this helpful?

Superior Product at. Price

4 stars out of a maximum of 5

This product is always highly recommended by skin care experts.  It does make a significant difference on skin clarity and radiance, but at a price.  My pet peeve is the packing.  I always find there is product left in many brands and I try to extract everything by uncapping bottles or cutting tubes.  But here it is impossible to get it open.  I just like to make sure I have used all of this product.

by Diane Verified Purchase

Was this helpful?

It works, however…

5 stars out of a maximum of 5

I am very skeptical, but, I admit it does work…as much as an anti-aging serum can anyway. You can see a little difference. It doesn’t mesh well with most of my moisturizers however, & will ball up. It’s very expensive so I use auto replenish for the discount.  I’m thinking of switching to a retinol though bc I can’t afford both, 

by Joy Verified Purchase

Was this helpful?

a tip for users

5 stars out of a maximum of 5

Hello! I already wrote a glowing review... but I wanted to add that I followed another reviewers advice about storing the product upside down. I am doing that and I have not had a problem at all with the 2 pumps providing the same amount of product each time. One of the serums is clear, though, while the other is white. So it may look like an unequal amount is being dispensed. I am continuing to enjoy the benefits of this great, but pricey, serum!

by gina Verified Purchase

Was this helpful?