First Time Orders Get Free Shipping on ANY purchase + TWO FREE Gifts with any $200+ purchase. SHOP NOW.
FREE US Shipping on First Order Auto-Replenishment 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

A retinol-based treatment to improve the skin's tone and texture.

Rewards members earn 960 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$96.00

Or 4 interest free payments of $24.00 with sezzle


In stock | Usually dispatched within 24 hours

Image 1 - Two side-by-side photographs of a 45-year-old woman showing her face at baseline and after 12 weeks of treatment, with visible text including Baseline and Week 12, along with details about skin type and treatment.
Image 2 - Image of SkinMedica skincare products arranged in a line, including an AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Retinol, HA+ Hydra Collagen Hydrator, and Essential Defense Mineral Shield Sunscreen, with the text Complete Your SkinMedica® Method Routine at the top.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

This item

SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

$96.00

Total Price:

$176.00

Other Customers Bought

Customer Reviews

4.82 stars out of a maximum of 5

5 stars rating 312 reviews

4 stars rating 35 reviews

3 stars rating 3 reviews

2 stars rating 2 reviews

1 stars rating 4 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Gave me a rash

2 stars out of a maximum of 5

I wanted so bad to love this ! But sadly it gave me a rash all over my face . I will be sending it back . Be careful if you have sensitive skin you may also get a rash

by Angela Verified Purchase

Was this helpful?

Amazingly Potent

5 stars out of a maximum of 5

I had been using another 1% retinol product before starting this one, so I was shocked at all the peeling I have experienced with this product. It is so potent! I love the texture. I have only been using it a couple months so can't speak to collagen production just yet, but it very quickly made my skin fresher, clearer and smoother, and my pores smaller. Healing from the occasional spot is rapid with this stuff. I'm still experiencing a bit of peeling, actually, and I even use this on top of a moisturizer. It's possible the effects are intensified because I use Biologique Recherche P50 1970 as well (just once a day), but I also suspect it might be due to the other goodies in this complex that boost the retinol's effects. In any case, I love this retinol and doubt whether I will need to transition to tretinoin at all within the next decade, or ever. This product seems powerful enough for me. It is quite amazing. Get it! Now!

by Anonymous Verified Purchase

Was this helpful?

Too harsh for sensitive skin

5 stars out of a maximum of 5

Ive used SkinMedica Retinol for 3 years now and I love the brand and their retinol formulations. Started with the 0.25 formula and then moved to 0.5. Once i felt my skin could handle the 0.5 i thought of using the 1.0 but it was way too strong for my skin. Their product is great but i would not recommend for sensitive skin as it can cause burning. Anyone looking to try this product, i would start with the 0.25 and move up to see what your skin can handle. I am sticking to the 0.5 and am happy with the results. Its definitely a quality retinol and if your skin can handle it i am sure you will notice clearer skin and less lines.

by Anonymous Verified Purchase

Was this helpful?

Effective

5 stars out of a maximum of 5

I have used retinol for 12 years, this is by far the best, very strong though, I can only use 3x per week and must use a good moisturizer

by Anonymous Verified Purchase

Was this helpful?

A HOLY GRAIL RETINOL

5 stars out of a maximum of 5

Quit scrolling at reviews and just buy the dang retinol! Your skin will thank you later - trust me. It might be a hefty price tag for only 1fl oz, but this is sent from the gods. Liquid gold in a bottle. After ONE USE I noticed change in my skin. I had never used a retinol before, only ones from Sephora. Which are nothing compared to medical grade retinol. So if you're debating on which brand, I would highly suggest SkinMedica. They are the best in the buz for skincare products that are medical grade. Though, I would warn you, to start the retinol 1x/week for a month, then increase to 2x/week the following month, and so on. I'm so glad my esthetician gave me that tip because otherwise I would've been peeling more than I already am! Im on month 3 now and I notice an overall brightness happening. My pores are slowly shrinking and I cant wait to see whats going to happen when I start using it every night! Just do it - its worth the $$$!

by Lohren Verified Purchase

Was this helpful?

Results after three days

5 stars out of a maximum of 5

Wow, this is amazing stuff. I have used it three nights and my skin is already sloughing. I will pull back to every two days because it is very potent but this is exactly what I expected so I am THRILLED my expectations were met. Retinol will cause irritation so if you have highly sensitive skin, maybe use the .5. I have always had "rough" skin so the higher concentration works for my skin but it may not be for everyone. Highly recommend.

by Anonymous Verified Purchase

Was this helpful?

I love this retinol

5 stars out of a maximum of 5

I've tried a few different retinol products, but I always come back to this one . It's very effective and leaves my skin looking so smooth. A little goes a long way with this product as well.

by Anonymous Verified Purchase

Was this helpful?

Love this product!

5 stars out of a maximum of 5

I swear by this product and will always continue to use it every night. People are always telling me how young I look and I believe it's from using this product since I was 30 years old and am now 54! Love it!!!!

by Anonymous Verified Purchase

Was this helpful?

A+ Retinol product

5 stars out of a maximum of 5

I have tried a variety of retinol products high end to mid range and none of them compare to this Skin Medica. Love the feel of it, soaks in quick, not sticky or silicone-feeling. Results were noticeable within a few weeks.

by Stacey Verified Purchase

Was this helpful?

Very Potent But Very Effective

5 stars out of a maximum of 5

I've been an avid OTC retinol user for years, and this is truly one of the most potent of them all. I started out 2 nights in a row and had some flaking and peeling. Then I pulled back and started using it every 2 nights for a few weeks because this stuff is incredibly strong. Now I'm using it every other night and my skin is really starting to look great! I use a really good night cream when I use this and also add in a face oil to keep moisturized. If you're new to retinol, I would suggest starting out with a lower concentration and slowly working your way up. As with any new skincare regimen, give it time. The results will be glowing!

by Marie Verified Purchase

Was this helpful?