25% OFF SkinMedica + An Extra 20% OFF Auto-Replenishment. SHOP NOW
FREE US Shipping $50+ Ask an Expert 15% off first App Order Dermstore Rewards Refer a Friend, Get $25
SkinMedica

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

A retinol-based, night lotion for first-time users of all skin types.

Rewards members earn 240 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

RRP: $64.00 Current price: $48.00

Save $ 16.00 ( 25% Off )

Or 4 interest free payments of $12.00 with afterpay


In stock | Usually dispatched within 24 hours


Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

This item

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

RRP: $64.00 Current price: $48.00

Save $16.00 ( 25% Off )

Total Price:

$108.00

Other Customers Bought

Customer Reviews

4.79

274 reviews

5

4

3

2

1

235

29

4

3

3

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

great product

I started using this product and after a few weeks noticed my skin tone was more even, the small little bumps on my forehead were gone. I absolutely love this product and will continue to use it.

by Doreida Verified Purchase

Was this helpful?

Great starter

I’m turning 40 this year and know I need to incorporate retinol into my routine. For whatever reason I’ve never added this product to the slew of others I’m diligent about. I’ve had no problems with this using it 3x’s a week now to build up using every other day to daily. 

by MinSRQ Verified Purchase

Was this helpful?

Great product!

Very effective and non-irritating. Luxurious feeling and absorbs quickly. (Unfortunately I accidentally dropped it and the bottle broke in half). I'm looking forward to trying other products in the Skin Medica line.

by Jo Verified Purchase

Was this helpful?

Gentle and effective

I find the other formulas to be too much for my skin.  The .25 does not irritate or “burn” my skin.  I have been using it every night with no issues.  

by Natalie Verified Purchase

Was this helpful?

The best!

I have incredibly sensitive skin. I cannot use Tretinoin and most retinols because they cause a painful contact dermatitis breakout.  BUT, this SkinMedica 0.25 Retinol Complex does the exact opposite. It softens and smooths my complexion in ways I only imagined. When I started using it I put a cream on first and then the retinol. Now that my skin is used to it, I put it down first and follow with a SkinMedica face cream. I use it every night, and I just love it! I’m soon going to try the next level SkinMedica 0.5 Retinol Complex. 

by Berry Verified Purchase

Was this helpful?

Perfect starter retinol

This is the perfect addition to my skin care routine. Not super drying or irritating. 

by Mary Verified Purchase

Was this helpful?

New skin

I'm in my early 20's and have been looking to update my skincare routine beyond the basics of cleanser, toner, and moisturizer. This product came highly recommended by my dermatologist who possesses flawless skin. Following the initial peeling phase in the first few months of incorporating retinol into my routine—a normal adjustment period—my skin has noticeably brightened, and my sun-induced freckles have faded. I am in love with this product and will be repurchasing when it runs out!

by Camille Verified Purchase

Was this helpful?

No irritation so far

It has not caused any irritation so far. I cannot speak to the effectiveness at this point since I have only used this for about two weeks. 

by Anna Verified Purchase

Was this helpful?

So far so good

Takes a while for your skin to get used to it, but eventually it does. It goes on nicely, doesn't smell and I'm able to use it with other hydrating products.

by Regina Verified Purchase

Was this helpful?

Great product

I was unable to use .5 because I have sensitive skin. So I tried the .25 and after a few months I am able to use it every day. It does not dry my skin out and has definitely helped improve skin texture and elasticity. I will continue using this product And recommend to others 

by Kristin Verified Purchase

Was this helpful?