Get It In Time: Order by 12/19 With Express Shipping. SHOP NOW
FREE US Shipping $50+ Ask an Expert 15% off first App Order Dermstore Rewards Refer a Friend, Get $50
iS Clinical

iS Clinical Active Serum (1 oz.)

A multi-tasking face serum that improves the appearance of aging, acne-prone and dull complexions.

Rewards members earn 710 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$142.00

Or 4 interest free payments of $35.50 with afterpay


In stock | Usually dispatched within 24 hours


Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

iS Clinical Active Serum (1 oz.)

This item

iS Clinical Active Serum (1 oz.)

$142.00

Total Price:

$230.00

Other Customers Bought

Customer Reviews

4.64

513 reviews

5

4

3

2

1

414

46

30

11

12

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Essential Part of My Nighttime Routine

I have comedonal acne (small bumps/clogged pores under the skin) around my Tzone and chin. This helps bring them to the surface gently. I have sensitive skin and this product works well with it since retinols even at a low potency can be too harsh. I've been using it for a year, every other night and have seen improvement in my skin clarity.

by Minnie Verified Purchase

Was this helpful?

PL

This is always a staple in my skin care line up! Leaves skin looking clean and great for breakouts . My pores hate this stuff bc it cleans them so well! 

by Product Lover Verified Purchase

Was this helpful?

Holy grail!

I’ve been using this serum for almost 10 years and will never go without it!  It’s the one consistent product in my skincare routine that keeps my pores small and breakouts minimal. While the cost might seem like a lot, the bottle lasts at least 6 months if you use the product correctly! I typically use it in my nighttime routine and will put about 4-5 drops in my palm then use my finger to tap it around my face and neck. If you’re going to implement any product into your routine I highly suggest this one!

by Karlie Verified Purchase

Was this helpful?

Great

A bit pricey but it worth. I have been using this with combination of Is Clinical Hydra- Cool Serum for few years. I’m at my 50, good to maintain.

by Sandy Verified Purchase

Was this helpful?

Tried & True

I had cystic acne for years when I started combining the active serum with my retinol i finally saw results that lasted. Don’t get me wrong I will still occasionally get a hormonal cystic pimple. But a little extra active right on the blemish fades and heals everything so nicely. Will always have Active Serum in my line up! 

by Rachel Verified Purchase

Was this helpful?

A must have for your skin care routine!

I’ve been using IS Clinical for a number of years.  The Active Serum is a must have.  It helps with fine lines, skin clarity & brightness.  It is a must have in your skin care routine!

by Mary Verified Purchase

Was this helpful?

Holy grail

I try everything as a beauty and product junkie, but this is so effective I have bought it over and over again.  It helps with blemishes, it helps with signs of aging, I love it.

by Katherine Verified Purchase

Was this helpful?

the best

i use this as a spot treatment on any blemish or soon-to-be blemish and it almost always is able to help it and minimize - if not completely get rid of!

by Brianne Verified Purchase

Was this helpful?

Active Serum

I started using this in the evening on nights I’m not doing retinal. The serum is very thin but applies well and gives my skin a tingly feeling. The next morning, I’ve noticed my skin looks very clear, my pores are not as visible, and I have a nice glow. I haven’t decided if it’s worth the cost, but so far I really like the results. 

by Jenna

Was this helpful?

Best Active Serum

This is always my go to serum for hormonal acne. Can use nightly.

by Chani Verified Purchase

Was this helpful?