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Shop our bestsellers now to upgrade your routine with beauty's most efficacious formulas and tools.

La Roche-Posay Hyalu B5 Hyaluronic Acid Serum (Various Sizes)

4.56 stars out of a maximum of 5

16 reviews

$39.99

Dr. Dennis Gross Skincare Alpha Beta Extra Strength Daily Peel (Pack of 60)

4.84 stars out of a maximum of 5

49 reviews

$153.00

Dr Dennis Gross Alpha Beta Universal Daily Peel (30 Pack)

4.88 stars out of a maximum of 5

17 reviews

$92.00

neuLash neuBROW Brow Enhancing Serum 3.6ml

5 stars out of a maximum of 5

1 reviews

$85.00

Neocutis BIO SERUM FIRM Rejuvenating Growth Factor & Peptide Treatment (1 fl. oz.)

4.66 stars out of a maximum of 5

97 reviews

$290.00

Eminence Organic Skin Care Clear Skin Probiotic Cleanser 8.4 fl. oz

4.62 stars out of a maximum of 5

262 reviews

$48.00

PCA SKIN ExLinea Peptide Smoothing Serum (1 fl. oz.)

4.63 stars out of a maximum of 5

119 reviews

$123.00

Paula's Choice SKIN BALANCING Pore-Reducing Toner (6.4 fl. oz.)

4.45 stars out of a maximum of 5

71 reviews

$26.00

Obagi Medical Obagi-C Fx System C-Clarifying Serum (1 oz.)

4.56 stars out of a maximum of 5

41 reviews

$140.00

Sunday Riley C.E.O. 15% Vitamin C Brightening Serum 1 fl. oz

4.38 stars out of a maximum of 5

356 reviews

$85.00

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2897 results

The Cyber Monday Skin Care Sale | Up to 30% off or 2x Points Has Ended

The sale may be over but get your favorites on Auto-Replenishment & never run out of your favorites *Hint: There maybe savings on our top brands*

15% Off20% Off25% Off30% OffMakeup Hair CareFragranceTools & DevicesLuxury BeautyGift SetsBestsellers
Epionce Lytic Tx (1.4 fl. oz.)

4.74 stars out of a maximum of 5

53 reviews

RRP: $56.00Current price: $44.80
PCA SKIN Vitamin B3 Brightening Serum (1 fl. oz.)

4.64 stars out of a maximum of 5

47 reviews

$128.00

Eminence Organic Skin Care Clear Skin Probiotic Moisturizer 2 fl. oz

4.55 stars out of a maximum of 5

231 reviews

$65.00

Medik8 Crystal Retinal 20 30ml

4.88 stars out of a maximum of 5

8 reviews

$121.00

Eminence Organic Skin Care Strawberry Rhubarb Dermafoliant

4.65 stars out of a maximum of 5

224 reviews

$55.00

PCA SKIN Pigment Gel Pro

4.67 stars out of a maximum of 5

6 reviews

$128.00

PCA SKIN Hydrator Plus Broad Spectrum SPF 30 (1.7 fl. oz.)

4.84 stars out of a maximum of 5

25 reviews

$50.00

PCA SKIN BPO 5 Percent Cleanser (7 oz.)

4.77 stars out of a maximum of 5

138 reviews

$46.00

SkinMedica Total Defense + Repair SPF 34 (2.3 oz.)

4.61 stars out of a maximum of 5

88 reviews

$70.00

EltaMD Clear Skin Daily Duo Kit

5 stars out of a maximum of 5

1 reviews

$82.00

Eminence Organic Skin Care Stone Crop Gel Wash 4.2 fl. oz

4.77 stars out of a maximum of 5

235 reviews

$48.00

iS Clinical Youth Eye Complex (0.5 oz.)

4.5 stars out of a maximum of 5

120 reviews

$120.00

Medik8 Advanced Night Ceramide Cream 48g

4.56 stars out of a maximum of 5

16 reviews

$76.00

Avène Tolerance Control Soothing Skin Recovery Cream for Sensitive Skin (1.35 oz.)

5 stars out of a maximum of 5

5 reviews

$38.00

Dermalogica AGE Smart Renewal Lip Complex (0.06 fl. oz.)

4.57 stars out of a maximum of 5

116 reviews

$31.00

Paula's Choice CLINICAL Niacinamide 20% Treatment (0.67 fl. oz.)

4.53 stars out of a maximum of 5

57 reviews

$55.00

Revision Skincare® Intellishade TruPhysical (1.7 oz.)

4.55 stars out of a maximum of 5

42 reviews

$86.00

La Roche-Posay Anthelios Tinted Mineral Light Fluid SPF 50 (Various Shades)

4.48 stars out of a maximum of 5

21 reviews

$39.99

Eminence Organic Skin Care Mangosteen Daily Resurfacing Cleanser 4.2 fl. oz

4.6 stars out of a maximum of 5

132 reviews

$48.00

PCA SKIN Daily Exfoliant (7 fl. oz.)

4.56 stars out of a maximum of 5

27 reviews

$48.00

iS Clinical Active Serum (0.5 oz.)

4.86 stars out of a maximum of 5

7 reviews

$92.00

La Roche-Posay Toleriane Purifying Foaming Cleanser (Various Sizes)

4.81 stars out of a maximum of 5

111 reviews

$17.99

SkinMedica AHA/BHA Cream (2 oz.)

4.74 stars out of a maximum of 5

138 reviews

$46.00

PCA SKIN Silkcoat Balm (1.7 oz.)

4.52 stars out of a maximum of 5

60 reviews

$61.00

PCA SKIN Daily Cleansing Oil (5 fl. oz.)

4.66 stars out of a maximum of 5

47 reviews

$46.00

Epionce Milky Lotion Cleanser (6 oz.)

4.84 stars out of a maximum of 5

50 reviews

$36.00

Obagi Medical Daily Hydro-Drops Facial Serum (1 oz.)

4.41 stars out of a maximum of 5

68 reviews

$110.00

Eminence Organic Skin Care Calm Skin Chamomile Moisturizer 2 fl. oz

4.62 stars out of a maximum of 5

69 reviews

$65.00

La Roche-Posay Toleriane Double Repair Moisturizer (Various Sizes)

4 stars out of a maximum of 5

1 reviews

$10.99

PCA SKIN Ideal Complex Revitalizing Eye Gel (0.5 oz.)

4.44 stars out of a maximum of 5

32 reviews

$104.00

La Roche-Posay Effaclar Adapalene Gel 0.1% Retinoid Acne Treatment (1.6 oz.)

4.75 stars out of a maximum of 5

57 reviews

$35.99

Obagi Medical CLENZIderm M.D. Daily Care Foaming Cleanser (4 oz.)

5 stars out of a maximum of 5

5 reviews

$49.00

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Unlock transformative skincare this Black Friday with our exclusive deals at Dermstore. Explore a selection of dermatologist-approved products that emphasize both effective and safe ingredients. Our curated range features hard-to-find dermatology and spa items that deliver purposeful innovation and remarkable results. Don’t miss these Black Friday skin care deals—invest in your skincare routine with products designed to elevate your beauty experience and reveal your healthiest skin!